Insights into the Localization of mRNA free essay sample

A review on an article discussing the insights into the localization of mRNA in embryonic and differentiated mammalian cells as it pertains to how proteins that mRNA code for are localized, modified and expressed. This paper reveals the increasing importance of mRNA study in understanding protein synthesis, localization and expression. It discusses the cellular mechanisms and techniques for measuring them. The writer explores the observed effects on development to the differentiation of the most complex cells and concludes that mRNA localization has proven to be a highly conserved and important mechanism in the cell. When cells are dividing and differentiating into tissues and higher complex structures, each tissue-type cell is uniquely characterized by the membrane bound and cytoplasmic proteins it contains. These various proteins are sequestered within the cell by various mechanisms. The details associated with protein targeting have been the focus of considerable research in the last decade. As a result, a good deal is known about protein sorting signals and the machinery needed for endo and exocytosis as well as the mechanisms for transporting vesicles along microtubules and actin filaments within the cytoplasm. We will write a custom essay sample on Insights into the Localization of mRNA or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page However, less is known about how cytosolic proteins are parceled out within the cytoplasm. It has become increasingly clear that the transport and localization of mRNA, not the proteins alone, plays an important role in the localization of proteins. mRNA localization is an active process highly conserved from a simple Drosophilia oocyte model to a very complex mammalian neuron. It allows for specificity in development and function that would otherwise not be possible.